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1. (WO2018099363) PHARMACEUTICAL COMPOSITION CONTAINING INSULIN-LIKE GROWTH FACTOR-2 AND USE THEREOF

Pub. No.:    WO/2018/099363    International Application No.:    PCT/CN2017/113341
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Wed Nov 29 00:59:59 CET 2017
IPC: A61K 38/30
A61K 35/15
A61K 45/06
A61P 37/04
A61P 37/02
A61P 1/00
A61P 25/28
A61P 1/16
A61P 19/02
A61P 5/50
A61P 3/10
C12N 5/0786
Applicants: SHANGAHI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES
中国科学院上海生命科学研究院
Inventors: SHI, Yufang
时玉舫
WANG, Ying
王莹
DU, Liming
杜黎明
LIN, Liangyu
林良宇
Title: PHARMACEUTICAL COMPOSITION CONTAINING INSULIN-LIKE GROWTH FACTOR-2 AND USE THEREOF
Abstract:
Provided is the use of an insulin-like growth factor-2 for preparing a pharmaceutical composition, wherein the pharmaceutical composition is used for (i) promoting the expression of the macrophage PD-L1, and/or (ii) inhibiting the expression of the macrophage IL-1β. Also provided is a pharmaceutical composition containing the insulin-like growth factor-2 as an active ingredient.