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|1. (WO2018099120) HEART RATE VARIABILITY ANALYSIS METHOD, DEVICE AND USE THEREOF|
BEIJING PINS MEDICAL CO., LTD
|Title:||HEART RATE VARIABILITY ANALYSIS METHOD, DEVICE AND USE THEREOF|
A heart rate variability analysis method, device and use thereof. The method comprises the following steps: (1) collecting electrocardiogram data in vitro; (2) digitizing the electrocardiogram data, and eliminating noises; (3) forming a sinus NN interval sequence from the treated electrocardiogram data; (4) respectively selecting sinus NN interval data in a long period of 20 hours or more, and sinus NN interval data in a short period of 2-10 minutes under each of an awake state and an asleep state; and (5) calculating at least one of the time domain, the frequency domain and the non-linear index of the sinus NN interval data in the long period of 20 hours or more, and sinus NN interval data in the short period of 2-10 minutes under each of the awake state and the asleep state. By calculating the time domain, the frequency domain and the non-linear index of the long period and short period ECGs using a stylized HRV analysis method, the effects of vagus nerve stimulation operation on a patient having medically intractable epileptic can be accurately and efficiently predicted, thus avoiding unnecessary expenses and preventing the patient from missing the optimal treatment opportunity.