Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018098636) POLYPEPTIDE AND APPLICATION THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/098636 International Application No.: PCT/CN2016/107751
Publication Date: 07.06.2018 International Filing Date: 29.11.2016
IPC:
C07K 7/06 (2006.01) ,C12N 15/52 (2006.01) ,C12N 15/63 (2006.01) ,C12N 5/22 (2006.01) ,C07K 16/00 (2006.01) ,A61K 38/08 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
52
Genes encoding for enzymes or proenzymes
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
12
Fused cells, e.g. hybridomas
22
Human cells
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08
Peptides having 5 to 11 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
深圳华大基因研究院 BGI SHENZHEN [CN/CN]; 中国广东省深圳市 盐田区北山工业区综合楼 Main Building, Beishan Industrial Zone, Yantian District Shenzhen, Guangdong 518083, CN
Inventors:
唐云霞 TANG, Yunxia; CN
李波 LI, Bo; CN
侯勇 HOU, Yong; CN
罗顺涛 LUO, Shuntao; CN
黄英 HUANG, Ying; CN
刘耿 LIU, Geng; CN
李冬丽 LI, Dongli; CN
林秀妹 LIN, Xiumei; CN
Agent:
北京清亦华知识产权代理事务所(普通合伙) TSINGYIHUA INTELLECTUAL PROPERTY LLC; 中国北京市 海淀区清华园清华大学照澜院商业楼301室 Room 301 Trade Building, Zhaolanyuan, Tsinghua University Qinghuayuan, Haidian District Beijing 100084, CN
Priority Data:
Title (EN) POLYPEPTIDE AND APPLICATION THEREOF
(FR) POLYPEPTIDE ET SON APPLICATION
(ZH) 多肽及其应用
Abstract:
(EN) The present invention provides a polypeptide. The present invention further provides a nucleic acid encoding the polypeptide, a nucleic acid construct comprising the nucleic acid, an expression vector, a host cell, and an antigen-presenting cell presenting the polypeptide on the surface of the cell as well as an immune effector cell thereof. The present invention further provides a pharmaceutical composition, a vaccine and an antibody comprising the polypeptide, a therapeutic method, a diagnosis method, and a diagnosis device. The present invention further provides use of the polypeptide in preparing a vaccine, a kit for tumor diagnosis or a pharmaceutical composition, and the use of the polypeptide and the nucleic acid serving as detection targets in tumor diagnosis.
(FR) La présente invention concerne un polypeptide. La présente invention concerne également un acide nucléique codant pour le polypeptide, une construction d'acide nucléique comprenant l'acide nucléique, un vecteur d'expression, une cellule hôte et une cellule présentatrice d'antigène présentant le polypeptide à la surface de la cellule ainsi qu'une cellule effectrice immunitaire de celle-ci. La présente invention concerne en outre une composition pharmaceutique, un vaccin et un anticorps comprenant le polypeptide, un procédé thérapeutique, un procédé de diagnostic et un dispositif de diagnostic. La présente invention concerne en outre l'utilisation du polypeptide dans la préparation d'un vaccin, un kit pour le diagnostic de tumeur ou une composition pharmaceutique, et l'utilisation du polypeptide et de l'acide nucléique servant de cibles de détection dans le diagnostic de tumeur.
(ZH) 本发明提供了一种多肽。本发明还提供了编码所述多肽的核酸、包含该核酸的核酸构建体、表达载体、宿主细胞,以及在细胞表面呈递该多肽的抗原呈递细胞及其免疫效应细胞。本发明还提供了包含该多肽的药物组合物、疫苗、抗体以及治疗方法、诊断方法和诊断装置。本发明还提供了所述多肽在用于制备疫苗、诊断肿瘤试剂盒或药物组合物中的用途,以及所述多肽、核酸作为检查靶标在肿瘤诊断中的用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)