Search International and National Patent Collections

1. (WO2018098534) METHODS OF TREATING CANCER AND REAGENTS THEREOF

Pub. No.:    WO/2018/098534    International Application No.:    PCT/AU2017/051327
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Tue Dec 05 00:59:59 CET 2017
IPC: A61K 31/519
A61K 31/192
A61K 31/496
A61K 31/506
A61K 31/54
A61K 38/17
A61K 48/00
A61P 35/04
Applicants: GARVAN INSTITUTE OF MEDICAL RESEARCH
Inventors: OAKES, Samantha R.
YOUNG, Adelaide Isobella Jane
ORMANDY, Christopher
Title: METHODS OF TREATING CANCER AND REAGENTS THEREOF
Abstract:
The present disclosure relates to methods of treating cancer and/or preventing metastasis thereof in subject suffering from cancer e.g., solid tumor cancers, and reagents therefor. The present disclosure also relates to methods of inhibiting or suppressing metastatic progression in a subject suffering from metastatic cancer e.g., a metastatic solid tumor cancer, and reagents therefor. In particular, the present disclosure relates to the use of compounds which inhibit MCL-1 activity for such treatment or prevention of cancer, including the use of such compounds in combination with other agents for treatment of cancer e.g., agents with inhibit activity of a SRC family kinase.