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|1. (WO2018098534) METHODS OF TREATING CANCER AND REAGENTS THEREOF|
|Applicants:||GARVAN INSTITUTE OF MEDICAL RESEARCH
|Inventors:||OAKES, Samantha R.
YOUNG, Adelaide Isobella Jane
|Title:||METHODS OF TREATING CANCER AND REAGENTS THEREOF|
The present disclosure relates to methods of treating cancer and/or preventing metastasis thereof in subject suffering from cancer e.g., solid tumor cancers, and reagents therefor. The present disclosure also relates to methods of inhibiting or suppressing metastatic progression in a subject suffering from metastatic cancer e.g., a metastatic solid tumor cancer, and reagents therefor. In particular, the present disclosure relates to the use of compounds which inhibit MCL-1 activity for such treatment or prevention of cancer, including the use of such compounds in combination with other agents for treatment of cancer e.g., agents with inhibit activity of a SRC family kinase.