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1. WO2018095345 - CRYSTAL FORM AND SALT FORM OF 7H-PYRROLO[2,3-D]PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR

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Publication Number WO/2018/095345
Publication Date 31.05.2018
International Application No. PCT/CN2017/112493
International Filing Date 23.11.2017
IPC
C07D 487/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/519 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61K 31/275 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
275Nitriles; Isonitriles
A61P 29/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
CPC
A61K 31/275
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
275Nitriles; Isonitriles
A61K 31/437
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
437the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
C07B 2200/07
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
07Optical isomers
Applicants
  • 无锡福祈制药有限公司 WUXI FORTUNE PHARMACEUTICAL CO.,LTD [CN]/[CN]
Inventors
  • 毛魏魏 MAO, Weiwei
  • 吴颢 WU, Hao
  • 郭强 GUO, Qiang
  • 郑学建 ZHENG, Xuejian
  • 廖勇刚 LIAO, Yonggang
Agents
  • 北京商专永信知识产权代理事务所（普通合伙） SBZL IP LAW OFFICE
Priority Data
201611046683.X23.11.2016CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) CRYSTAL FORM AND SALT FORM OF 7H-PYRROLO[2,3-D]PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR
(FR) FORME CRISTALLINE ET FORME SALINE DU COMPOSÉ 7H-PYRROLO [2,3-D] PYRIMIDINE ET SON PROCÉDÉ DE PRÉPARATION
(ZH) 一种7H-吡咯并[2,3-d]嘧啶类化合物的晶型、盐型及其制备方法
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Abstract
(EN) Disclosed are a crystal form and a salt form of 7H-pyrrolo[2,3-d]pyrimidine compound and a preparation method therefor, and the use of the crystal form and salt form in the preparation of a drug for treating arthritis.
(FR) L'invention concerne une forme cristalline et une forme saline du composé 7H-pyrrolo [2,3-d] pyrimidine et son procédé de préparation, et l'utilisation de la forme cristalline et de la forme saline dans la préparation d'un médicament pour le traitement de l'arthrite.
(ZH) 本发明公开了一种7H-吡咯并[2,3-d]嘧啶类化合物晶型、盐型及其制备方法，还包括所述晶型和盐型在制备治疗关节炎药物中的应用。
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