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1. (WO2018090052) BISPECIFIC OR BIPARATOPIC ANTIGEN BINDING PROTEINS AND USES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/090052 International Application No.: PCT/US2017/061636
Publication Date: 17.05.2018 International Filing Date: 14.11.2017
IPC:
C07K 16/28 (2006.01) ,C07K 16/40 (2006.01)
Applicants: AMGEN INC.[US/US]; One Amgen Center Drive Patent Operations, M/S 35-1-B Thousand Oaks, California 91320-1799, US
Inventors: YAN, Wei; US
LIU, Zhi; US
MURAWSKY, Christopher; CA
KING, Chadwick Terence; CA
LI, Yang; US
HU, Zhonghua; US
LIM, Desiree; CA
Agent: DERMOTT, Jonathan M.; US
Priority Data:
62/421,94714.11.2016US
Title (EN) BISPECIFIC OR BIPARATOPIC ANTIGEN BINDING PROTEINS AND USES THEREOF
(FR) PROTÉINES DE LIAISON À L'ANTIGÈNE BISPÉCIFIQUES OU BIPARATOPIQUES ET UTILISATIONS DE CELLES-CI
Abstract:
(EN) The present invention relates to bispecific or biparatopic antigen binding proteins, polynucleotides encoding the same, and methods of making bispecific or biparatopic antigen binding proteins. Also described herein is a method to assemble IgG-like biparatopic or bispecific antibodies from VH only antigen binding proteins.
(FR) La présente invention concerne des protéines de liaison à l'antigène bispécifiques ou biparatopiques, des polynucléotides codant pour celles-ci, et des procédés de fabrication de protéines de liaison à l'antigène bispécifiques ou biparatopiques. L'invention concerne également un procédé pour assembler des anticorps biparatopiques ou bispécifiques de type IgG à partir de protéines de liaison à l'antigène du VH.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)