Search International and National Patent Collections

1. (WO2018090028) COMPOSITIONS AND METHODS OF TREATING CANCER

Pub. No.:    WO/2018/090028    International Application No.:    PCT/US2017/061593
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Wed Nov 15 00:59:59 CET 2017
IPC: A61K 39/00
C12N 5/16
A61K 35/15
A61K 31/00
A61P 35/00
Applicants: DANA-FARBER CANCER INSTITUTE, INC.
BETH ISRAEL DEACONESS MEDICAL CENTER
Inventors: AVIGAN, David
ROSENBLATT, Jacalyn
KUFE, Donald
Title: COMPOSITIONS AND METHODS OF TREATING CANCER
Abstract:
The present invention provides compositions and methods for treating cancer, wherein the composition comprises: a. a population a cells comprising a dendritic cell/tumor cell fusion or a dendritic cell/extracellular vesicle fusion; and b. an indoleamine-2,3-dioxygenase (IDO) inhibitor and/or a hypomethylating agent (HMA).