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1. (WO2018089807) ANTI-CD46 ANTIBODIES AND METHODS OF USE

Pub. No.:    WO/2018/089807    International Application No.:    PCT/US2017/061124
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Sat Nov 11 00:59:59 CET 2017
IPC: A61K 39/395
A61P 35/00
C07K 16/28
C07K 16/30
C07K 16/46
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: LIU, Bin
SHERBENOU, Daniel W.
AFTAB, Blake T.
SU, Yang
BEHRENS, Christopher R.
Title: ANTI-CD46 ANTIBODIES AND METHODS OF USE
Abstract:
Disclosed herein are methods of treating a subject having a cancer characterized by a modification at biomarker 1q21, which comprises administering to the subject a therapeutically effective amount of an anti-CD46 antibody.