Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018089789) SYSTEM, METHOD AND BIOMARKERS FOR AIRWAY OBSTRUCTION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/089789 International Application No.: PCT/US2017/061099
Publication Date: 17.05.2018 International Filing Date: 10.11.2017
IPC:
A61B 5/024 (2006.01) ,A61B 5/0456 (2006.01) ,A61B 5/0488 (2006.01) ,A61B 5/08 (2006.01) ,A61B 5/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
024
Measuring pulse rate or heart rate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
0402
Electrocardiography, i.e. ECG
0452
Detecting specific parameters of the electrocardiograph cycle
0456
Detecting R peaks, e.g. for synchronising diagnostic apparatus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
0488
Electromyography
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
08
Measuring devices for evaluating the respiratory organs
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
Applicants:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK [US/US]; 450 Clarkson Avenue, Box 0128 Brooklyn, New York 11203, US
Inventors:
STEWART, Mark; US
KOLLMAR, Richard; US
LAZAR, Jason; US
Agent:
HOFFBERG, Steven; US
Priority Data:
62/420,30810.11.2016US
Title (EN) SYSTEM, METHOD AND BIOMARKERS FOR AIRWAY OBSTRUCTION
(FR) SYSTÈME, PROCÉDÉ ET BIOMARQUEURS D'OBSTRUCTION DES VOIES AÉRIENNES
Abstract:
(EN) Two biomarkers are provided for obstructive apnea. A first biomarker determines amplitude and timing of inspiratory efforts from a bioelectric signal. The respiratory rate is compared with a normal pre-detection rate, and the amplitude of the effort is compared with a normal amplitude. The obstructive apnea is likely present if a series of inspiratory efforts are above a normal amplitude and with increasing amplitude, but at a normal rate. A second biomarker determines heart rate and respiratory rate. A normal lower threshold for heartbeat interval is established, and if subthreshold events occur (short RR intervals), a commencement time for each sequence of subthreshold events is compared for a respiratory rate-normalized window. If the number of subthreshold events exceeds a minimum for the window, obstructive apnea is likely present.
(FR) L'invention porte sur deux biomarqueurs pour l'apnée obstructive. Un premier biomarqueur détermine l'amplitude et la synchronisation des efforts d'inspiration à partir d'un signal bioélectrique. La fréquence respiratoire (FR) est comparée à une fréquence de pré-détection normale, et l'amplitude des efforts est comparée à une amplitude normale. Il est probable que l'apnée obstructive est présente si une série d'efforts d'inspiration est d'une amplitude au-dessus d'une amplitude normale et qu'elle est croissante, tout en étant à une fréquence normale. Un second biomarqueur détermine la fréquence cardiaque et la fréquence respiratoire. Un seuil inférieur normal pour l'intervalle de battements de cœur est établi, et, si des événements de sous-seuil surviennent (intervalles de RR courts), un temps de commencement pour chaque séquence d'événements de sous-seuil est comparé pour une fenêtre normalisée de fréquence respiratoire. Si le nombre d'événements de sous-seuil dépasse un minimum pour la fenêtre, il est probable qu'une apnée obstructive est présente.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)