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1. (WO2018089592) COMPOSITIONS AND METHODS FOR TREATING HIV-1 LATENCY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/089592    International Application No.:    PCT/US2017/060791
Publication Date: 17.05.2018 International Filing Date: 09.11.2017
IPC:
A61K 31/706 (2006.01), A61K 35/14 (2015.01), C12N 5/0783 (2010.01), A61K 38/17 (2006.01)
Applicants: WASHINGTON UNIVERSITY [US/US]; One Brookings Drive St. Louis, Missouri 63130 (US) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JO, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
BARNES, Alexander, B. [US/US]; (US) (US only).
KYEI, George [US/US]; (US) (US only).
ALBERT, Brice [US/US]; (US) (US only)
Inventors: BARNES, Alexander, B.; (US).
KYEI, George; (US).
ALBERT, Brice; (US)
Agent: TIETZ, Paul, D.; (US).
AGOVINO, Frank, R.; (US).
BAIN, Robert, M.; (US).
CONWAY, Jason, H.; (US).
EVANS, Robert, M., Jr.; (US).
EVERDING, William, R.; (US).
FLEISCHUT, Paul, I. J.; (US).
GODAR, Michael, E.; (US).
HARTLEY, Michael, J.; (US).
KEIL, Vincent, M.; (US).
JAMES, Kurt, F.; (US).
JORDAN, Jamaal, R.; (US).
MILLARD, Elizabeth, E.; (US).
PETRILLO, Kathleen, M.; (US).
POLLMANN, Jonathan, G.; (US).
ROEDEL, John, K., Jr.; (US).
SCHROEDER, John, R.; (US).
VANDER TUIG, Marc, W.; (US).
WEGMAN, Andrew, C.; (US).
HENDRICKSON, Janet, S.; (US).
BARRINGER, Kyle, L.; (US).
JOHNSON, Morgan, L.; (US)
Priority Data:
62/419,849 09.11.2016 US
Title (EN) COMPOSITIONS AND METHODS FOR TREATING HIV-1 LATENCY
(FR) COMPOSITIONS ET MÉTHODES POUR TRAITER LA LATENCE DU VIH-1
Abstract: front page image
(EN)Pharmaceutical compositions comprising a combination of a Class I isoform-selective histone deacetylase inhibitor and a protein kinase C modulator are described as well as methods of using these compositions for treating HIV-1 latency.
(FR)L'invention concerne des compositions pharmaceutiques comprenant une combinaison d'un inhibiteur d'histone désacétylase sélective d'un isoforme de classe I et d'un modulateur de protéine kinase C, ainsi que des méthodes d'utilisation de ces compositions pour traiter la latence du VIH-1.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)