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1. (WO2018089554) PRE-ASSEMBLED, PROTECTED, CHEMICALLY STABLE, CHEMOSELECTIVE LINKERS
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Pub. No.: WO/2018/089554 International Application No.: PCT/US2017/060721
Publication Date: 17.05.2018 International Filing Date: 08.11.2017
IPC:
C07F 7/18 (2006.01) ,C07F 1/04 (2006.01) ,C07F 5/02 (2006.01) ,G01N 33/68 (2006.01)
[IPC code unknown for C07F 7/18][IPC code unknown for C07F 1/04][IPC code unknown for C07F 5/02][IPC code unknown for G01N 33/68]
Applicants:
HEALTHTELL INC. [US/US]; 2420 Camino Ramon Suite 125 San Ramon, California 94583, US
Inventors:
WALSH, Patrick; US
SMITH, David; US
SAINI, Gaurav; US
PARK, Jae H.; US
Agent:
WESTIN, Lorelei P.; US
Priority Data:
62/419,86109.11.2016US
Title (EN) PRE-ASSEMBLED, PROTECTED, CHEMICALLY STABLE, CHEMOSELECTIVE LINKERS
(FR) LIEURS CHIMIOSÉLECTIFS PRÉ-ASSEMBLÉS, PROTÉGÉS, CHIMIQUEMENT STABLES
Abstract:
(EN) Molecules compounds are provided having the structure in Formula I, or a salt thereof, wherein n1 is independently 0, 1, 2, or 3; n2 is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20; n3 is from 0, 1, 2, or 3; n4 is 0 or 1; and n5 is 0, 1, 2, or 3; and wherein X is O, N, or S; Y, Z, XX, and YY are the same or different and are independently O or S; ZZ comprises nitrogen, oxygen, sulfur, or selenium; and wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 are as described herein. Methods are also provided for the synthesis of and use of the provided molecules in applications for diagnostic testing.
(FR) L'invention concerne des composés de molécules ayant la structure dans la formule I, ou un sel de ceux-ci, où n1 est indépendamment 0, 1, 2 ou 3 ; n 2 est 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 ou 20 ; n 3 est 0, 1, 2 ou 3 ; n 4 est 0 ou 1 ; et n 5 est 0, 1, 2 ou 3 ; et X est O, N ou S ; Y, Z, XX, et YY sont identiques ou différents et représentent indépendamment O ou S ; ZZ comprend l'azote, l'oxygène, le soufre ou le sélénium ; et R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 étant tels que décrits dans la description. L'invention concerne également des procédés pour la synthèse et l'utilisation des molécules fournies dans des applications pour un test de diagnostic.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)