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1. (WO2018089467) METHODS FOR REDUCING RECURRENCE OF TUMORS

Pub. No.:    WO/2018/089467    International Application No.:    PCT/US2017/060599
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Thu Nov 09 00:59:59 CET 2017
IPC: A61K 31/54
A61K 31/19
A61K 31/415
Applicants: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
Inventors: SUKHATME, Vikas
PANIGRAHY, Dipak
Title: METHODS FOR REDUCING RECURRENCE OF TUMORS
Abstract:
Methods of reducing the risk of cancer after surgery, e.g., of cancer recurrence, by administering COX-1 selective inhibitors prior to surgery or biopsy. Alternatively or in addition, other anti-platelet agents and/or TGF-β inhibition and/or IL-6 inhibition and/or inhibitors of the PD-1/PD-L1 axis, as well as combinations thereof.