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1. (WO2018089465) NANOCARRIERS HAVING SURFACE CONJUGATED PEPTIDES AND USES THEREOF FOR SUSTAINED LOCAL RELEASE OF DRUGS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/089465    International Application No.:    PCT/US2017/060596
Publication Date: 17.05.2018 International Filing Date: 08.11.2017
IPC:
C07K 17/08 (2006.01), C07K 14/475 (2006.01), C07K 7/06 (2006.01), A61K 47/69 (2017.01), A61K 47/61 (2017.01), A61K 47/60 (2017.01), B82Y 5/00 (2011.01)
Applicants: NORTHWESTERN UNIVERSITY [US/US]; 633 Clark Street Evanston, IL 60208 (US)
Inventors: HENKIN, Jack; (US).
MELGAR-ASENSIO, Ignacio; (US)
Agent: STAPLE, David W.; (US).
OLEJNICZAK, Aaron, T.; (US).
KUBORN, Joseph, D.; (US).
TAKEN, Michael, E.; (US).
WILLIAMS, JR., Edward, J.; (US)
Priority Data:
62/420,344 10.11.2016 US
15/497,822 26.04.2017 US
PCT/US17/029618 26.04.2017 US
Title (EN) NANOCARRIERS HAVING SURFACE CONJUGATED PEPTIDES AND USES THEREOF FOR SUSTAINED LOCAL RELEASE OF DRUGS
(FR) NANO-PORTEURS AYANT DES PEPTIDES CONJUGUÉS EN SURFACE ET LEURS UTILISATIONS POUR UNE LIBÉRATION LOCALE PROLONGÉE DE MÉDICAMENTS
Abstract: front page image
(EN)Disclosed are biodegradable nanocarriers that have a net positive surface charge and zeta potential between about +2 to about +20 mV. The positive surface charge of the nanocarriers is provided by peptides that are covalently attached to the surface of the nanocarriers. The nanocarriers may comprise a drug and may be administered for localized and sustained delivery of the drug.
(FR)L'invention concerne des nano-porteurs biodégradables qui ont une charge de surface positive nette et un potentiel zêta entre environ +2 et environ +20 mV. La charge de surface positive des nano-porteurs est fournie par des peptides qui sont fixés de manière covalente à la surface des nano-porteurs. Les nano-porteurs peuvent comprendre un médicament et peuvent être administrés pour un apport localisé et prolongé du médicament.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)