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1. (WO2018089300) ILT3 LIGAND
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/089300 International Application No.: PCT/US2017/060154
Publication Date: 17.05.2018 International Filing Date: 06.11.2017
IPC:
A61K 39/00 (2006.01) ,C07K 16/28 (2006.01)
Applicants: CUA, Daniel[US/US]; US (US)
CHERWINSKI, Holly[US/US]; US (US)
WANG, Adele[US/US]; US (US)
CHEN, Yi[US/US]; US (US)
JOYCE-SHAIKH, Barbara[US/US]; US (US)
MERCK SHARP & DOHME CORP.[US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US
Inventors: CUA, Daniel; US
CHERWINSKI, Holly; US
WANG, Adele; US
CHEN, Yi; US
JOYCE-SHAIKH, Barbara; US
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US
Priority Data:
62/420,17310.11.2016US
Title (EN) ILT3 LIGAND
(FR) LIGAND ILT3
Abstract: front page image
(EN) The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.
(FR) La présente invention concerne des anticorps et des fragments de liaison à l'antigène de ceux-ci qui se lient à ILT3, un ligand ILT3 (c'est-à-dire PI16) ou un complexe formé entre ILT3 et le ligand ILT3. L'invention concerne également des procédés permettant de déterminer si ILT3 et le ligand ILT3 se lient ensemble ou si une substance a une action agoniste ou antagoniste relativement à une telle liaison.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)