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1. (WO2018089250) DEVICE AND METHOD FOR TEMPERATURE MODULATION OF THE NOSTRILS, NASAL CAVITY, AND ORAL ENTRANCE
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Pub. No.: WO/2018/089250 International Application No.: PCT/US2017/059741
Publication Date: 17.05.2018 International Filing Date: 02.11.2017
IPC:
A61F 7/12 (2006.01) ,A61B 18/02 (2006.01) ,A61F 7/00 (2006.01) ,F25B 17/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
7
Heating or cooling appliances for medical or therapeutic treatment of the human body
12
Devices for heating or cooling internal body cavities
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
18
Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
02
by cooling, e.g. cryogenic techniques
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
7
Heating or cooling appliances for medical or therapeutic treatment of the human body
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
25
REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION OR SOLIDIFICATION OF GASES
B
REFRIGERATION MACHINES, PLANTS, OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
17
Sorption machines, plant, or systems, operating intermittently, e.g. absorption or adsorption type
02
the absorbent or adsorbent being a liquid, e.g. brine
Applicants:
CEDARS-SINAI MEDICAL CENTER [US/US]; 8700 Beverly Blvd. Los Angeles, California 90048, US
Inventors:
ROSENGART, Axel; US
Agent:
BIRKENEDER, Erik, J.; US
VAKHARIA-RAO, Hema; US
CHEN, Stephen, W.; US
COSTELLIA, Jeffrey; US
EISENSTEIN, Ronald, I.; US
GARETTO, Janet, M.; US
GATZ, Robert; US
HUBER, Linda B.; US
KIM, Sean; US
LEVY, Seth D.; US
MATTAN-HUNG, Natalia; US
PROMMER, Peter J.; US
RESNICK, David S.; US
SWIATEK, Maria; US
TANG, Wayne L.; US
Priority Data:
62/420,06010.11.2016US
Title (EN) DEVICE AND METHOD FOR TEMPERATURE MODULATION OF THE NOSTRILS, NASAL CAVITY, AND ORAL ENTRANCE
(FR) DISPOSITIF ET PROCÉDÉ DE MODULATION DE TEMPÉRATURE DES NARINES, DE LA CAVITÉ NASALE ET DE L'ORIFICE BUCCAL
Abstract:
(EN) The disclosed devices and methods cool the nasal and / or oral cavity and perioral area, which in turn triggers a positive sensory reflex response to the brain leading to improvement of abnormally regulated cerebral vasomotor (brain arterial) tone which is thought to be the primary trigger factor for migraine headaches. Cooling is applied temporarily (10 to 30 minutes) to the inside of either or both nostrils. In some examples, the device is a single-use cooling "bullet" made from plastic (or other materials), has a conical, egg, nasal, oval, or other suitable shape and fits tightly to the inside of either nostril. The bullet may contain a nontoxic coolant (i.e., propylene glycol), water or other coolant which is kept at a cold state (e.g. 3-6 degrees Celsius below normal body temperature).
(FR) L'invention concerne des dispositifs et des procédés qui refroidissent la cavité nasale et/ou buccale et la zone perorale, ce qui déclenche une réponse réflexe sensorielle positive vers le cerveau entraînant l'amélioration d'une tonicité vasomotrice cérébrale (artérielle cérébrale) anormalement régulée qui est considérée comme étant le facteur de déclenchement primaire des céphalées migraineuses. Le refroidissement est appliqué temporairement (10 à 30 minutes) à l'intérieur de l'une ou des deux narines. Dans certains exemples, le dispositif est une "balle" de refroidissement à usage unique faite de plastique (ou d'autres matériaux), présente une forme conique, ovoïde, nasale, ovale, ou toute autre forme appropriée et s'adapte étroitement à l'intérieur de l'une ou l'autre narine. La balle peut contenir un agent de refroidissement non toxique (par exemple, du propylèneglycol), de l'eau ou un autre agent de refroidissement qui est maintenu à l'état froid (par exemple 3 à 6 degrés Celsius au-dessous de la température corporelle normale).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)