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1. (WO2018088856) MICROFLUIDIC CHIP, THREE-DIMENSIONAL CHANNEL STRUCTURE, CELL CULTURE METHOD USING SAME, AND ACTIVITY EVALUATION METHOD OF BIOACTIVE SUBSTANCE USING SAME
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Pub. No.: WO/2018/088856 International Application No.: PCT/KR2017/012763
Publication Date: 17.05.2018 International Filing Date: 10.11.2017
IPC:
C12M 1/32 (2006.01) ,C12M 3/06 (2006.01) ,C12M 1/26 (2006.01) ,C12N 5/09 (2010.01)
Applicants: THE ASAN FOUNDATION[KR/KR]; 88, Olympic-ro 43-gil Songpa-gu Seoul 05505, KR
UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION[KR/KR]; 93, Daehak-ro Nam-gu Ulsan 44610, KR
Inventors: JEONG, Gi Seok; KR
HWANG, Changmo; KR
JANG, Se-Jin; KR
Agent: FIRSTLAW P.C.; 60, Mabang-Ro Seocho-Ku Seoul 06775, KR
Priority Data:
10-2016-014979810.11.2016KR
Title (EN) MICROFLUIDIC CHIP, THREE-DIMENSIONAL CHANNEL STRUCTURE, CELL CULTURE METHOD USING SAME, AND ACTIVITY EVALUATION METHOD OF BIOACTIVE SUBSTANCE USING SAME
(FR) PUCE MICROFLUIDIQUE, STRUCTURE DE CANAL TRIDIMENSIONNELLE, PROCÉDÉ DE CULTURE CELLULAIRE UTILISANT CELLE-CI ET PROCÉDÉ D'ÉVALUATION D'ACTIVITÉ D'UNE SUBSTANCE BIOACTIVE UTILISANT CELLE-CI
(KO) 마이크로유체칩, 삼차원 채널 구조물, 이를 이용한 세포 배양 방법 및 이를 이용한 생리활성 물질의 활성평가 방법
Abstract: front page image
(EN) A microfluidic chip according to an embodiment of the present invention comprises: a plate; a bridge channel formed in intaglio on one face of the plate; an entrance part formed through the plate so as to communicate with an end of one side of the bridge channel; an exit part formed through the plate so as to communicate with an end of the other side of the bridge channel; and at least one well extending in an outward direction of the plate from the bridge channel to provide a space. The bridge channel may be formed to have a shape of a curve, a bent line, an arc, a circle, a spiral, or a polygon.
(FR) Selon un mode de réalisation de l'invention, une puce microfluidique comprend : une plaque; un canal de pont formé en creux sur une face de la plaque; une partie d'entrée formée par la plaque de façon à communiquer avec une extrémité d'un côté du canal de pont; une partie de sortie formée par la plaque de façon à communiquer avec une extrémité de l'autre côté du canal de pont; et au moins un puits s'étendant vers l'extérieur de la plaque à partir du canal de pont pour fournir un espace. Le canal de pont peut être réalisé de façon à avoir une forme de courbe, de ligne courbée, d'arc, de cercle, de spirale ou de polygone.
(KO) 본 발명의 일 실시예에 따른 마이크로유체칩은 플레이트, 플레이트의 일면에 음각으로 형성되는 브릿지 채널, 브릿지 채널의 일측 단부와 연통하도록 플레이트를 관통하여 형성되는 유입부, 브릿지 채널의 타측 단부와 연통하도록 플레이트를 관통하여 형성되는 배출부 및 브릿지 채널로부터 플레이트의 외측 방향으로 연장되어 공간을 제공하는 적어도 하나의 웰을 포함하고, 브릿지 채널은 곡선, 꺽인선, 호형, 원형, 나선형 또는 다각형으로 형성될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)