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1. (WO2018088826) COMPOSITION FOR DIAGNOSING COLORECTAL CANCER METASTASIS OR PREDICTING PROGNOSIS AND USE THEREOF
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Pub. No.: WO/2018/088826 International Application No.: PCT/KR2017/012691
Publication Date: 17.05.2018 International Filing Date: 09.11.2017
IPC:
G01N 33/574 (2006.01) ,G01N 33/573 (2006.01) ,C12Q 1/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
573
for enzymes or isoenzymes
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
한국생명공학연구원 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY [KR/KR]; 대전시 유성구 과학로 125 125, Gwahak-ro, Yuseong-gu, Daejeon 34141, KR
Inventors:
김남순 KIM, Nam Soon; KR
전수영 JUN, Soo Young; KR
조현수 CHO, Hyun Soo; KR
이정주 LEE, Jeong Ju; KR
이용재 LEE, Yong Jae; KR
민주식 MIN, Ju Sik; KR
안준호 AHN, Jun Ho; KR
윤지용 YOON, Ji Yong; KR
전수진 JEON, Su Jin; KR
정초록 JUNG, Cho Rok; KR
최민혁 CHOI, Min Hyeok; KR
Agent:
손민 SON, Min; KR
Priority Data:
10-2016-014893009.11.2016KR
Title (EN) COMPOSITION FOR DIAGNOSING COLORECTAL CANCER METASTASIS OR PREDICTING PROGNOSIS AND USE THEREOF
(FR) COMPOSITION DE DIAGNOSTIC DE MÉTASTASES DU CANCER COLORECTAL OU DE PRÉDICTION DE PRONOSTIC ET SON UTILISATION
(KO) 대장암 전이 진단 또는 예후 예측용 조성물 및 이의 용도
Abstract:
(EN) In the present invention, a colorectal cancer metastasis diagnosing composition comprising squalene epoxidase and/or a reagent for measuring an mRNA or protein level of p53 gene can be used to diagnose colorectal cancer metastasis and/or to predict the prognosis of colorectal cancer.
(FR) La présente invention concerne une composition de diagnostic de métastases du cancer colorectal comprenant de la squalène époxydase et/ou un réactif permettant de mesurer un ARNm ou un niveau de protéine du gène p53, pouvant être utilisée pour diagnostiquer des métastases du cancer colorectal et/ou pour prédire le pronostic du cancer colorectal.
(KO) 본 발명에서는 스쿠알렌 에폭시다제(squalene epoxidase) 및/또는 p53 유전자의 mRNA 또는 이의 단백질의 수준을 측정하는 제제를 포함하는 대장암 전이 진단용 조성물을 이용하여, 대장암 전이를 진단 및/또는 대장암의 예후를 예측할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)