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1. (WO2018088272) ENDOTHELIN-CONVERTING ENZYME INHIBITOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/088272 International Application No.: PCT/JP2017/039319
Publication Date: 17.05.2018 International Filing Date: 31.10.2017
IPC:
A61K 36/81 (2006.01) ,A61K 36/90 (2006.01) ,A61K 36/185 (2006.01) ,A61K 36/48 (2006.01) ,A61K 36/67 (2006.01) ,A61P 9/12 (2006.01) ,A61P 17/18 (2006.01) ,A61Q 19/02 (2006.01) ,A61K 8/97 (2017.01) ,A61K 36/899 (2006.01)
Applicants: KAO CORPORATION[JP/JP]; 14-10, Nihonbashi Kayabacho 1-chome, Chuo-ku, Tokyo 1038210, JP
CHULALONGKORN UNIVERSITY[TH/TH]; 254, Phyathai Road, Wangmai, Pathumwan,Bangkok 10330, TH
Inventors: HASHIMOTO, Hiroshi; TH
HOTTA, Mitsuyuki; JP
BOONSRI, Ongpipattanakul; TH
RUTT, Suttisri; TH
CHUTIMA, Petchprayoon; TH
WORATUCH, Thitikornpong; TH
Agent: THE PATENT CORPORATE BODY ARUGA PATENT OFFICE; Sawanotsuru Ningyocho Bldg., 1-3-8, Nihonbashi Ningyocho, Chuo-ku, Tokyo 1030013, JP
Priority Data:
PCT/JP2016/08318109.11.2016JP
Title (EN) ENDOTHELIN-CONVERTING ENZYME INHIBITOR
(FR) INHIBITEUR D'ENZYME DE CONVERSION D'ENDOTHÉLINE
Abstract:
(EN) Provision of a material, which has activity of inhibiting endothelin-converting enzyme and is effective for skin whitening or antihypertension. An endothelin-converting enzyme inhibitor comprising, as an active ingredient, at least one selected from the group consisting of Hiptage candicans, Piper sarmentosum, Solanum stramonifolium, Anaxagorea luzonensis, Smilax corbularia, Ardisia elliptica, Erythrina suberosa, Dactyloctenium aegyptium, Hopea ferrea and extracts thereof.
(FR) La présente invention a pour objet de fournir un matériau, qui présente une activité d'inhibition d'enzyme de conversion d'endothéline et est efficace pour le blanchiment de la peau ou la lutte contre l'hypertension. Un inhibiteur d'enzyme de conversion d'endothéline comprend, en tant que principe actif, au moins un élément choisi dans le groupe constitué par Hiptage candicans, Piper sarmentosum, Solanum stramonifolium, Anaxagorea luzonensis, Smilax corbularia, Ardisia elliptica, Erythrina suberosa, Dactyloctenium aegyptium, Hopea ferrea et leurs extraits.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)