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1. (WO2018087641) COMPOSITIONS AND METHODS FOR INHIBITING GROWTH OF ACSL4-OVEREXPRESSING TUMORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/087641 International Application No.: PCT/IB2017/056879
Publication Date: 17.05.2018 International Filing Date: 03.11.2017
IPC:
A61K 31/15 (2006.01) ,A61K 31/337 (2006.01) ,A61K 31/4439 (2006.01) ,A61K 31/704 (2006.01) ,A61K 45/06 (2006.01) ,A61P 35/00 (2006.01)
Applicants: PODESTA, Ernesto J.[IT/AR]; AR
CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)[AR/AR]; Godoy Cruz 2290 Ciudad Autónoma de Buenos Aires C1425FQB, AR
Inventors: PODESTA, Ernesto J.; AR
CASTILLO, Ana F.; AR
ORLANDO, Ulises D.; AR
MALOBERTI, Paula M.; AR
SOLANO, Angela R.; AR
Priority Data:
62/419,01308.11.2016US
Title (EN) COMPOSITIONS AND METHODS FOR INHIBITING GROWTH OF ACSL4-OVEREXPRESSING TUMORS
(FR) COMPOSITIONS ET PROCÉDÉS POUR L'INHIBITION DE LA CROISSANCE DE TUMEURS SUREXPRIMANT L'ACSL4
Abstract:
(EN) Compositions and methods for inhibiting tumor growth, particularly breast cancer, in a combined pharmacological treatment. A pharmaceutical combination for inhibiting growth of a tumor overexpressing ACSL4, comprising a first and a second dosage forms, wherein: i) the first dosage form comprises an ACSL4 inhibitor; and ii) the second dosage form comprises a chemotherapeutic agent.
(FR) L'invention concerne des compositions et des procédés pour l'inhibition de la croissance de tumeurs, en particulier d'un cancer du sein, dans un traitement pharmacologique combiné. Plus précisément, l'invention concerne une association pharmaceutique pour l'inhibition de la croissance d'une tumeur surexprimant l'ACSL4, comprenant des première et seconde formes pharmaceutiques : i) la première forme pharmaceutique comprenant un inhibiteur de l'ACSL4 ; et ii) la seconde forme pharmaceutique comprenant un agent chimiothérapeutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)