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1. (WO2018087345) COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON

Pub. No.:    WO/2018/087345    International Application No.:    PCT/EP2017/078974
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Tue Nov 14 00:59:59 CET 2017
IPC: A61K 38/21
A61K 31/4745
A61K 31/522
A61P 31/20
Applicants: F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
Inventors: JAVANBAKHT, Hassan
WILDUM, Steffen
Title: COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON
Abstract:
The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBs Ag inhibitor, a nucleos(t)ide analogue and an interferon for use in the treatment or prophylaxis of chronic Hepatitis B virus infections.