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1. (WO2018087109) MULTIPARTICULATE DOSAGE FORM WITH CONTROLLED RELEASE OF METAMIZOL
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Pub. No.: WO/2018/087109 International Application No.: PCT/EP2017/078525
Publication Date: 17.05.2018 International Filing Date: 08.11.2017
Chapter 2 Demand Filed: 30.08.2018
IPC:
A61K 9/16 (2006.01) ,A61K 9/50 (2006.01) ,A61K 31/4152 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
415
1,2-Diazoles
4152
having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
Applicants:
GRÜNENTHAL GMBH [DE/DE]; Zieglerstraße 6 52078 Aachen, DE
Inventors:
SCHILLER, Marc; DE
VAN HEMELRIJCK, Carlos; DE
OEDEKOVEN, Karl-Heinz; DE
EBNER, Elisabeth; DE
Agent:
KUTZENBERGER WOLFF & PARTNER; Waidmarkt 11 50676 Cologne, DE
Priority Data:
16197675.808.11.2016EP
Title (EN) MULTIPARTICULATE DOSAGE FORM WITH CONTROLLED RELEASE OF METAMIZOL
(FR) FORME GALÉNIQUE MULTIPARTICULAIRE À LIBÉRATION DE MÉTAMIZOLE CONTRÔLÉE
(DE) MULTIPARTIKULÄRE ARZNEIFORM MIT KONTROLLIERTER FREISETZUNG VON METAMIZOL
Abstract:
(EN) The invention relates to a pharmaceutical composition containing metamizol or a physiologically acceptable salt thereof as an active ingredient, wherein the composition comprises a plurality of particles, each of which comprise a core which is coated with a retarding coating, wherein the active ingredient is contained in the core and is released under physiological conditions in a controlled manner from the particles.
(FR) L'invention concerne une composition pharmaceutique qui comprend en tant que principe actif du métamizole ou un de ses sels physiologiquement acceptables, ladite composition comprenant une pluralité de particules comprenant respectivement un cœur qui est recouvert d'un enrobage gastro-résistant, le principe actif étant contenu dans le cœur et libéré de manière contrôlée hors des particules dans des conditions physiologiques.
(DE) Die Erfindung betrifft eine pharmazeutische Zusammensetzung, welche als Wirkstoff Metamizol oder eines seiner physiologisch verträglichen Salze umfasst, wobei die Zusammensetzung eine Vielzahl von Partikeln umfasst, welche jeweils einen Kern umfassen, welcher mit einem retardierenden Überzug beschichtet ist, wobei der Wirkstoff in dem Kern enthalten ist und unter physiologischen Bedingungen kontrolliertaus den Partikelnfreigesetzt wird.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)