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1. (WO2018087092) NITRIC OXIDE RELEASING PROSTAGLANDIN DERIVATIVES FOR TREATING NORMAL TENSION GLAUCOMA
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Pub. No.: WO/2018/087092 International Application No.: PCT/EP2017/078486
Publication Date: 17.05.2018 International Filing Date: 07.11.2017
IPC:
A61K 31/5575 (2006.01) ,A61P 27/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
557
Eicosanoids, e.g. leukotrienes
5575
having a cyclopentane ring, e.g. prostaglandin E2, prostaglandin F2-alpha
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27
Drugs for disorders of the senses
02
Ophthalmic agents
06
Antiglaucoma agents or miotics
Applicants:
BAUSCH & LOMB INCORPORATED [US/US]; 1400 North Goodman Street Rochester, New York 14609, US
NICOX S.A. [FR/FR]; Drakkar 2, Bat D, 2405 Route des Dolines 06560 CS 10313 - SOPHIA ANTIPOLIS - VALBONNE, FR
Inventors:
VITTITOW, Jason Lamar; US
CAVET, Megan Elizabeth; US
Agent:
BARCHIELLI, Giovanna; IT
Priority Data:
62/419,15308.11.2016US
Title (EN) NITRIC OXIDE RELEASING PROSTAGLANDIN DERIVATIVES FOR TREATING NORMAL TENSION GLAUCOMA
(FR) DÉRIVÉS DE PROSTAGLANDINE LIBÉRANT DE L'OXYDE NITRIQUE POUR LE TRAITEMENT DU GLAUCOME À TENSION NORMALE
Abstract:
(EN) This invention provides a method of lowering intraocular pressure in a patient having normal tension glaucoma, comprising contacting an eye of a subject having normal tension glaucoma with a pharmaceutical composition comprising an effective amount of Nitric Oxide releasing prostaglandin derivatives of formula (I).
(FR) La présente invention concerne un procédé d'abaissement de la pression intraoculaire chez un patient ayant un glaucome à tension normale, comprenant la mise en contact d'un œil d'un sujet ayant un glaucome à tension normale avec une composition pharmaceutique comprenant une quantité efficace de dérivés de prostaglandine libérant de l'oxyde nitrique de formule (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)