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1. (WO2018086791) SCALABLE PROCESS FOR ONCOLYTIC RAT PARVOVIRUS H-1 PRODUCTION AND PURIFICATION BASED ON ISOELECTRIC POINT-BASED ELIMINATION OF EMPTY PARTICLES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/086791    International Application No.:    PCT/EP2017/073639
Publication Date: 17.05.2018 International Filing Date: 19.09.2017
IPC:
C12N 7/00 (2006.01)
Applicants: DEUTSCHES KREBSFORSCHUNGSZENTRUM [DE/DE]; Im Neuenheimer Feld 69120 Heidelberg (DE)
Inventors: LEUCHS, Barbara; (DE).
ROMMELAERE, Jean; (DE).
FREHTMAN, Veronika; (DE).
RIESE, Markus; (DE)
Agent: SCHÜSSLER, Andrea; Huber & Schüssler Truderinger Strasse 246 81825 Munich (DE)
Priority Data:
16198026.3 09.11.2016 EP
Title (EN) SCALABLE PROCESS FOR ONCOLYTIC RAT PARVOVIRUS H-1 PRODUCTION AND PURIFICATION BASED ON ISOELECTRIC POINT-BASED ELIMINATION OF EMPTY PARTICLES
(FR) PROCÉDÉ ÉVOLUTIF POUR LA PRODUCTION ET LA PURIFICATION DE PARVOVIRUS H-1 ONCOLYTIQUE DE RAT SUR LA BASE DE L'ÉLIMINATION BASÉE SUR UN POINT ISOÉLECTRIQUE DE PARTICULES VIDES
Abstract: front page image
(EN)The present invention provides a reproducible, effective and scalable process for the purification of (infectious) parvovirus H-1 particles. The purification process allows the separation of empty particles from particles containing a full genome and is compatible with large-scale H-1PV production for clinical applications.
(FR)La présente invention concerne un procédé reproductible, efficace et évolutif pour la purification de particules de parvovirus H-1 (infectieuses). Le procédé de purification permet la séparation de particules vides de particules contenant un génome complet et est compatible avec la production de PV H-1 à grande échelle pour des applications cliniques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)