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1. (WO2018086703) DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/086703    International Application No.:    PCT/EP2016/077449
Publication Date: 17.05.2018 International Filing Date: 11.11.2016
IPC:
C07D 471/04 (2006.01), C07D 487/04 (2006.01), A61P 35/00 (2006.01), A61K 31/501 (2006.01), A61K 31/5377 (2006.01), A61K 31/519 (2006.01)
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT [DE/DE]; Müllerstr. 178 13353 Berlin (DE)
Inventors: GIESE, Anja; (DE).
QUANZ-SCHOEFFEL, Maria; (DE).
MÜLLER, Thomas; (DE).
GÜNTHER, Judith; (DE).
BÖHNKE, Niels; (DE).
GRIEBENOW, Nils; (DE).
BARAK, Naomi; (DE).
BÖMER, Ulf; (DE).
NEUHAUS, Roland; (DE).
OSMERS, Maren; (DE).
KOPITZ, Charlotte Christine; (DE).
KAULFUSS, Stefan; (DE).
REHWINKEL, Hartmut; (DE).
WEISKE, Jörg; (DE).
BADER, Benjamin; (DE).
CHRISTIAN, Sven; (DE).
HILLIG, Roman; (DE)
Agent: BIP PATENTS; c/o Bayer Intellectual Property GmbH Alfred-Nobel-Str. 10 40789 Monheim am Rhein (DE)
Priority Data:
Title (EN) DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS
(FR) DIHYDROPYRIDAZINONES SUBSTITUÉES PAR DES PHÉNYLURÉES
Abstract: front page image
(EN)Compounds of formula (I) which are nicotinamide phosphoribosyltransferase (NAMPT) inhibitors and their use for the treatment of hyperproloferative diseases and/or disorders responsive to induction of cell death.
(FR)L'invention concerne des composés de formule (I) qui sont des inhibiteurs de nicotinamide phosphoribosyltransférase (NAMPT) et leur utilisation pour le traitement de maladies et/ou de troubles hyperprolifératifs sensibles à l'induction de la mort cellulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)