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1. (WO2018086703) DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS

Pub. No.:    WO/2018/086703    International Application No.:    PCT/EP2016/077449
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Sat Nov 12 00:59:59 CET 2016
IPC: C07D 471/04
C07D 487/04
A61P 35/00
A61K 31/501
A61K 31/5377
A61K 31/519
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT
Inventors: GIESE, Anja
QUANZ-SCHOEFFEL, Maria
MÜLLER, Thomas
GÜNTHER, Judith
BÖHNKE, Niels
GRIEBENOW, Nils
BARAK, Naomi
BÖMER, Ulf
NEUHAUS, Roland
OSMERS, Maren
KOPITZ, Charlotte Christine
KAULFUSS, Stefan
REHWINKEL, Hartmut
WEISKE, Jörg
BADER, Benjamin
CHRISTIAN, Sven
HILLIG, Roman
Title: DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS
Abstract:
Compounds of formula (I) which are nicotinamide phosphoribosyltransferase (NAMPT) inhibitors and their use for the treatment of hyperproloferative diseases and/or disorders responsive to induction of cell death.