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1. (WO2018086599) ANTI-H7N9 FULLY-HUMAN MONOCLONAL ANTIBODY 5J13, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
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Pub. No.: WO/2018/086599 International Application No.: PCT/CN2017/110506
Publication Date: 17.05.2018 International Filing Date: 10.11.2017
IPC:
C07K 16/10 (2006.01) ,C12N 15/13 (2006.01) ,A61K 39/42 (2006.01) ,A61P 31/16 (2006.01) ,G01N 33/577 (2006.01)
Applicants: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY[CN/CN]; 1068, Xueyuan Avenue, Xili University Town, Nanshan Shenzhen, Guangdong 518055, CN
Inventors: WAN, Xiaochun; CN
LI, Junxin; CN
LIU, Lvyan; CN
Agent: BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD.; 16th Fl., Block A, Corporate Square, No.35 Jinrong Street Beijing 100033, CN
Priority Data:
201611038444.X11.11.2016CN
Title (EN) ANTI-H7N9 FULLY-HUMAN MONOCLONAL ANTIBODY 5J13, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
(FR) ANTICORPS MONOCLONAL 5J13 ANTI-H7N9 ENTIÈREMENT HUMAIN, SON PROCÉDÉ DE PRÉPARATION ET SON APPLICATION
(ZH) 抗H7N9全人源单克隆抗体5J13及其制法与应用
Abstract:
(EN) The present application provides an anti-H7N9 fully-human monoclonal antibody 5J13, a preparation method therefor, and an application thereof. The antibody can perform target binding with hemagglutinin HA of H7N9 virus, and has neutralization activity of anti-H7N9 virus infection and good biocompatibility.
(FR) La présente invention concerne un anticorps monoclonal 5J13 anti-H7N9 entièrement humain, son procédé de préparation et son application. L'anticorps peut effectuer une liaison cible avec l'hémagglutinine HA du virus H7N9, et présente une activité de neutralisation de l'infection par le virus anti-H7N9 et une bonne biocompatibilité.
(ZH) 本申请提供了一种抗H7N9全人源单克隆抗体5J13及其制备方法与应用。所述抗体可靶向结合H7N9病毒的血凝素HA,具有抗H7N9病毒感染的中和活性,较好的生物相容性。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)