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1. (WO2018086594) GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC TIM-3
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/086594 International Application No.: PCT/CN2017/110494
Publication Date: 17.05.2018 International Filing Date: 10.11.2017
IPC:
A01K 67/00 (2006.01) ,C12N 15/63 (2006.01) ,C12N 15/00 (2006.01) ,C12N 15/09 (2006.01)
Applicants: BEIJING BIOCYTOGEN CO., LTD[CN/CN]; Room 1201-1210 Building 3, No. 88 Kechuang 6 Street, BDA Beijing 101111, CN
Inventors: SHEN, Yuelei; CN
NI, Jian; CN
GUO, Yanan; CN
HUANG, Rui; CN
ZHANG, Meiling; CN
ZHAO, Lei; CN
BAI, Yang; CN
Agent: BEIJING LINKTEC IP LAW AGENT (SPECIAL GENERAL PARTNER); Room 108 No. 9 West Apartment No. 56 Zhichun Road, Haidian District Beijing 100086, CN
Priority Data:
201610994218.211.11.2016CN
201711103773.210.11.2017CN
Title (EN) GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC TIM-3
(FR) ANIMAL NON HUMAIN GÉNÉTIQUEMENT MODIFIÉ AVEC UNE TIM-3 HUMAINE OU CHIMÉRIQUE
Abstract: front page image
(EN) Disclosed herein are genetically modified non-human animals that express a human or chimeric (e.g., humanized) T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), and methods of use thereof.
(FR) L'invention concerne des animaux non humains génétiquement modifiés qui expriment une TIM-3, molécule de type immunoglobuline des lymphocytes T contenant des mucines, humaine ou chimérique (par exemple, humanisée), et des procédé d'utilisation de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)