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1. (WO2018086550) BIOLOGICAL ACTIVE COMPONENT COLON-TARGETED COMPOSITION AND APPLICATION THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/086550 International Application No.: PCT/CN2017/110074
Publication Date: 17.05.2018 International Filing Date: 09.11.2017
IPC:
A61K 9/20 (2006.01) ,A61K 47/38 (2006.01) ,A61K 35/747 (2015.01) ,A61K 35/745 (2015.01) ,A61P 1/00 (2006.01) ,A23L 33/135 (2016.01)
Applicants: NANJING HEALSOUL LIFE SCIENCE AND TECHNOLOGY CO., LTD.[CN/CN]; Room 307, 26 Majia Street, Gulou District Nanjing, Jiangsu 210009, CN
Inventors: ZHANG, Junshou; CN
SUN, Chaonan; CN
ZHANG, Hao; CN
Agent: BOSS & YOUNG PATENT & TRADEMARK LAW OFFICE; 5/F., Tower A, Bldg. No. 1, GT International Center Jia 3 Yongandongli, Jianguomenwai Avenue Chaoyang District, Beijing 100022, CN
Priority Data:
201611013848.311.11.2016CN
Title (EN) BIOLOGICAL ACTIVE COMPONENT COLON-TARGETED COMPOSITION AND APPLICATION THEREOF
(FR) COMPOSITION CONTENANT UN COMPOSANT ACTIF BIOLOGIQUE CIBLANT LE CÔLON ET SON APPLICATION
(ZH) 一种生物学活性组分结肠靶向组合物及其应用
Abstract:
(EN) A biological active component colon-targeted composition, preparations thereof and a preparation method therefor. The biological active component colon-targeted composition comprises in weight percentage: 10-99% hydroxypropyl methylcellulose, 1-60% biological active component, and 0-80% adjuvant, wherein the viscosity of hydroxypropyl methylcellulose is greater than 1,000 mPa•S. The biological active component colon-targeted composition has an improved colon-targeted effect and improves the bioavailability and in vivo activity of the biological active component.
(FR) L'invention concerne une composition contenant un composant actif biologique, ciblant le côlon, des préparations de celle-ci et un procédé de préparation associé. La composition contenant un composant actif biologique, ciblant le côlon comprend en pourcentage en poids : de 10 à 99 % d'hydroxypropylméthylcellulose, de 1 à 60 % de composant actif biologique, et de 0 à 80 % d'adjuvant, la viscosité de l'hydroxypropylméthylcellulose étant supérieure à 1000 mPa•S. la composition ciblant le côlon contenant un composant actif biologique présente un effet amélioré ciblé sur le côlon et améliore la biodisponibilité et l'activité in vivo du composant actif biologique.
(ZH) 一种生物学活性组分结肠靶向组合物及其制剂和制备方法,该生物学活性组分结肠靶向组合物包括:重量百分含量为10-99%的羟丙甲纤维素、重量百分含量为1-60%的生物学活性组分和重量百分含量为0-80%的辅料,其中羟丙甲纤维素的粘度>1000mPa.s。该生物学活性组分结肠靶向组合物具有改进的结肠靶向效果,提高了生物学活性组分的生物利用度和体内活性。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)