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1. (WO2018086540) HAEMADIPSA SYLVESTRIS ANTITHROMBOTIC PEPTIDE SYLVESTIN AND USE THEREOF

Pub. No.:    WO/2018/086540    International Application No.:    PCT/CN2017/109962
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Thu Nov 09 00:59:59 CET 2017
IPC: C07K 14/815
C12N 15/15
A61K 38/58
A61P 7/02
A61P 9/10
Applicants: KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
中国科学院昆明动物研究所
KUNMING LONGJIN PHARMACEUTICAL CO., LTD
昆明龙津药业股份有限公司
Inventors: LAI, Ren
赖仞
LIU, Weihui
刘伟慧
LONG, Chengbo
龙承波
LV, Qiumin
吕秋敏
Title: HAEMADIPSA SYLVESTRIS ANTITHROMBOTIC PEPTIDE SYLVESTIN AND USE THEREOF
Abstract:
Provided are a Haemadipsa sylvestris antithrombotic peptide sylvestin and the use thereof, falling within the technical field of biomedicine. The Haemadipsa sylvestris antithrombotic peptide sylvestin can inhibit FXIIa and kallikrein, has anti-thrombus/infarction effects and alleviates injuries caused by cerebral ischemia, and can also be used in the preparation of inhibitors of FXIIa and kallikrein and drugs for anti-thrombus/infarction and anti-cerebral ischemic injuries.