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1. (WO2018085967) GENETICALLY HUMANIZED MAMMALS EXPRESSING HUMAN SERUM ALBUMIN AND USES THEREOF

Pub. No.:    WO/2018/085967    International Application No.:    PCT/CN2016/104956
Publication Date: Fri May 18 01:59:59 CEST 2018 International Filing Date: Wed Nov 09 00:59:59 CET 2016
IPC: C12N 15/14
C07K 14/765
Applicants: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES
Inventors: LAI, Liangxue
Title: GENETICALLY HUMANIZED MAMMALS EXPRESSING HUMAN SERUM ALBUMIN AND USES THEREOF
Abstract:
Genetically humanized mammals expressing human albumin and uses thereof. In some embodiments, the genome of the non-human transgenic mammal includes a polynucleotide sequence encoding human albumin, which may include a modification of human albumin gene.