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1. (WO2018085937) MANAGING SITE SPECIFIC IBD IMMUNOTHERAPIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/085937    International Application No.:    PCT/CA2017/051344
Publication Date: 17.05.2018 International Filing Date: 10.11.2017
IPC:
C12Q 1/68 (2018.01), A61K 39/00 (2006.01), A61P 1/00 (2006.01), A61P 37/04 (2006.01), C12Q 1/6809 (2018.01), C12Q 1/6827 (2018.01), C12Q 1/6858 (2018.01), G01N 33/48 (2006.01), C40B 30/04 (2006.01)
Applicants: QU BIOLOGICS INC. [CA/CA]; 305-4475 Wayburne Drive Burnaby, British Columbia V5G 4X4 (CA)
Inventors: GUNN, Harold David; (CA).
MULLINS, David W.; (US).
KALYAN, Shirin; (CA).
BOSILJCIC, Momir; (CA).
ZHANG, Monan Angela; (CA).
BAZETT, Mark; (CA).
THALEN, Marcel; (CA).
MCGOVERN, Dermot; (US).
KABAKCHIEV, Boyko Traychev; (CA).
SHAM, Ho Pan; (CA)
Agent: KINGWELL, Brian; (CA).
ZIESCHE, Sonia; (CA).
SECHLEY, Konrad; (CA).
WILKE, Mark; (CA).
THORNE, Lisa; (CA).
RIPLEY, Roch; (CA).
LEE, Brian; (CA).
FERANCE, Stephen; (CA).
SALISBURY, Clare; (CA)
Priority Data:
62/421,511 14.11.2016 US
62/442,759 05.01.2017 US
62/457,618 10.02.2017 US
62/472,394 16.03.2017 US
PCT/CA2017/050513 26.04.2017 CA
62/564,063 27.09.2017 US
Title (EN) MANAGING SITE SPECIFIC IBD IMMUNOTHERAPIES
(FR) GESTION D'IMMUNOTHÉRAPIES IBD SPÉCIFIQUES À UN SITE
Abstract: front page image
(EN)Methods are provided for predicting the degree to which a patient has a likelihood of benefiting from treatment with an antigenic formulation comprising PRR agonists. Methods may include screening a sample isolated from said patient for a genomic polymorphism that is a diagnostic SNP, or is in genetic linkage disequilibrium with the diagnostic SNP. In some instances, the subject has an increased likelihood of benefiting from a treatment if the diagnostic SNP comprises a selected response allele.
(FR)L'invention concerne des procédés permettant de prédire le degré auquel un patient a une probabilité de bénéficier d'un traitement avec une formulation antigénique comprenant des agonistes de PRR. Les procédés peuvent comprendre le criblage d'un échantillon isolé dudit patient pour un polymorphisme génomique qui est un SNP de diagnostic, ou est en déséquilibre de liaison génétique avec le SNP de diagnostic. Dans certains cas, le sujet présente une probabilité accrue de bénéficier d'un traitement si le SNP de diagnostic comprend un allèle de réponse sélectionné.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)