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1. (WO2018085833) SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASE 5 (PRMT5)
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/085833 International Application No.: PCT/US2017/060396
Publication Date: 11.05.2018 International Filing Date: 07.11.2017
IPC:
C07D 487/04 (2006.01) ,A61K 31/70 (2006.01) ,C07H 19/14 (2006.01) ,C07H 19/167 (2006.01)
Applicants: PRELUDE THERAPEUTICS, INCORPORATED[US/US]; 550 S. College Avenue, Suite 110 Newark, DE 19713, US
Inventors: LUENGO, Juan; US
LEAL, Raul, A.; US
LIN, Hong; US
SHETTY, Rupa; US
Agent: DOYLE, Timothy, J.; US
LODISE, Stephanie, A.; US
Priority Data:
62/418,54107.11.2016US
Title (EN) SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASE 5 (PRMT5)
(FR) INHIBITEURS SÉLECTIFS DE LA PROTÉINE ARGININE MÉTHYLTRANSFÉRASE 5 (PRMT5)
Abstract: front page image
(EN) The disclosure is directed to compounds of Formula I, Formula II, and Formula III [Formulas should be inserted here]. Methods of their use and preparation are also described.
(FR) L'invention concerne des composés de formule I, de formule II et de formule III. L'invention concerne également des procédés d'utilisation et de préparation de ces composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)