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1. (WO2018085833) SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASE 5 (PRMT5)

Pub. No.:    WO/2018/085833    International Application No.:    PCT/US2017/060396
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Wed Nov 08 00:59:59 CET 2017
IPC: C07D 487/04
A61K 31/70
C07H 19/14
C07H 19/167
Applicants: PRELUDE THERAPEUTICS, INCORPORATED
Inventors: LUENGO, Juan
LEAL, Raul, A.
LIN, Hong
SHETTY, Rupa
Title: SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASE 5 (PRMT5)
Abstract:
The disclosure is directed to compounds of Formula I, Formula II, and Formula III [Formulas should be inserted here]. Methods of their use and preparation are also described.