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1. (WO2018085440) REDUCTION AND PREVENTION OF MUSCLE LOSS BY CONJUGATED LINOLEIC ACID (CLA) AND VITAMIN D

Pub. No.:    WO/2018/085440    International Application No.:    PCT/US2017/059585
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Thu Nov 02 00:59:59 CET 2017
IPC: A61K 31/201
A61K 31/592
A61K 31/593
A61P 3/02
Applicants: BASF CORPORATION
BASF SE
Inventors: MORITZ, Joseph, M.
SCHMELLER, Thorsten
KAMPMANN, Mareike, Katharina
Title: REDUCTION AND PREVENTION OF MUSCLE LOSS BY CONJUGATED LINOLEIC ACID (CLA) AND VITAMIN D
Abstract:
Disclosed herein include compositions comprising conjugated linoleic acid (CLA) and vitamin D, and the uses thereof. Methods of administering CLA and vitamin D to a subject are also provided in some embodiments. Vitamin D and CLA can be co-administered to reduce and prevent muscle loss, for example age-related loss of muscle mass and functions. Co-administration of vitamin D and CLA can have a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.