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1. (WO2018085375) METHODS FOR THE IODINATION OF BIOMOLECULES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/085375 International Application No.: PCT/US2017/059503
Publication Date: 11.05.2018 International Filing Date: 01.11.2017
IPC:
C07K 1/107 (2006.01) ,C07K 1/13 (2006.01) ,G01N 33/532 (2006.01)
Applicants: OHIO STATE INNOVATION FOUNDATION[US/US]; 1524 North High Street Columbus, Ohio 43201, US
Inventors: KUMAR, Krishan; US
Agent: ZUCCHERO, Anthony J.; US
HUFF, Jason D.; US
HALL, Miles E.; US
MEUNIER, Andrew T.; US
CARLIN, Gregory J.; US
CURFMAN, Christopher L.; US
Priority Data:
62/415,87101.11.2016US
Title (EN) METHODS FOR THE IODINATION OF BIOMOLECULES
(FR) PROCÉDÉS D'IODATION DE BIOMOLÉCULES
Abstract:
(EN) Provided herein are methods for iodinating biomolecules, including proteins and peptides. The methods can be used to successfully and efficiently iodinate biomolecules under relatively mild reaction conditions. As a consequence, the methods described herein can be used to iodinate biomolecules that include, for example, an oxidatively unstable moiety (e.g., an optical dye) without adversely impacting the oxidatively unstable moiety.
(FR) L'invention concerne des procédés d'iodation de biomolécules, y compris des protéines et des peptides. Les procédés peuvent être utilisés pour ioder avec succès et efficacement des biomolécules dans des conditions de réaction relativement modérées. Par conséquent, les procédés décrits ici peuvent être utilisés pour ioder des biomolécules qui comprennent, par exemple, une fraction instable par oxydation (par exemple, un colorant optique) sans avoir un effet négatif sur la fraction instable par oxydation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)