Search International and National Patent Collections

1. (WO2018084650) VECTOR FOR EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR OR SKIN-PERMEABLE HUMAN EPIDERMAL GROWTH FACTOR, AND MICROALGAE TRANSFORMED WITH VECTOR

Pub. No.:    WO/2018/084650    International Application No.:    PCT/KR2017/012437
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Sat Nov 04 00:59:59 CET 2017
IPC: C12N 15/79
C12P 21/00
C07K 14/485
A61K 8/64
A61Q 19/00
A61Q 19/08
Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
한국과학기술연구원
Inventors: PAN, Cheol-Ho
판철호
SHIN, Bok-Kyu
신복규
ERDENE-OCHIR, Erdenedolgor
에르덴-오치르에르덴돌고르
KIM, Sang Min
김상민
Title: VECTOR FOR EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR OR SKIN-PERMEABLE HUMAN EPIDERMAL GROWTH FACTOR, AND MICROALGAE TRANSFORMED WITH VECTOR
Abstract:
The present specification relates to: a vector comprising a promoter of SEQ ID NO: 1 and a human epidermal growth factor (hEGF) exon, which includes a gene coding for hEGF; microalgae transformed with the vector; a method for producing a hEGF protein and/or a PTD-hEGF protein by using the transformed microalgae; and a cosmetic composition containing the hEGF and/or PTD-hEGF protein(s) produced according to the production method. The hEGF and PTD-hEGF proteins, produced according to an aspect of the present invention, can fundamentally block the risk of endotoxicity, unlike a hEGF protein produced from conventional E. coli, thereby being usable as a raw material for eco-friendly cosmetic products.