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|1. (WO2018084650) VECTOR FOR EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR OR SKIN-PERMEABLE HUMAN EPIDERMAL GROWTH FACTOR, AND MICROALGAE TRANSFORMED WITH VECTOR|
|Applicants:||KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
KIM, Sang Min
|Title:||VECTOR FOR EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR OR SKIN-PERMEABLE HUMAN EPIDERMAL GROWTH FACTOR, AND MICROALGAE TRANSFORMED WITH VECTOR|
The present specification relates to: a vector comprising a promoter of SEQ ID NO: 1 and a human epidermal growth factor (hEGF) exon, which includes a gene coding for hEGF; microalgae transformed with the vector; a method for producing a hEGF protein and/or a PTD-hEGF protein by using the transformed microalgae; and a cosmetic composition containing the hEGF and/or PTD-hEGF protein(s) produced according to the production method. The hEGF and PTD-hEGF proteins, produced according to an aspect of the present invention, can fundamentally block the risk of endotoxicity, unlike a hEGF protein produced from conventional E. coli, thereby being usable as a raw material for eco-friendly cosmetic products.