Search International and National Patent Collections

1. (WO2018084607) BIOTHIOL DETECTING COMPOSITION COMPRISING REDOX REGULATION PROTEIN

Pub. No.:    WO/2018/084607    International Application No.:    PCT/KR2017/012344
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Fri Nov 03 00:59:59 CET 2017
IPC: G01N 33/536
G01N 33/68
G01N 33/533
Applicants: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
한양대학교 산학협력단
Inventors: KIM, Young-Pil
김영필
LEE, Jin Oh
이진오
LEE, Jin-Won
이진원
YANG, Yoon Mo
양윤모
KIM, Tae-Wuk
김태욱
Title: BIOTHIOL DETECTING COMPOSITION COMPRISING REDOX REGULATION PROTEIN
Abstract:
The present invention relates to a biothiol detecting composition comprising a redox regulation protein, a method for detecting biothiols by using the same, and a biosensor/kit for detecting biothiols. The present invention provides the effect of rapidly measuring free biothiols in body fluids. In addition, relative content ratios and changes of total to free biothiols in body fluids can be detected in real time, which allows biothiols to be available as main indices of diseases through which prediction and warning can be made against various diseases. Further, because various redox stress changes associated with main diseases can be accounted for by variations of biothiols, the present invention can provide important technical, economical, and social values for the investigation of pathogenesis mechanisms and the diagnosis of diseases in the future.