Search International and National Patent Collections
|1. (WO2018084607) BIOTHIOL DETECTING COMPOSITION COMPRISING REDOX REGULATION PROTEIN|
|Applicants:||INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
LEE, Jin Oh
YANG, Yoon Mo
|Title:||BIOTHIOL DETECTING COMPOSITION COMPRISING REDOX REGULATION PROTEIN|
The present invention relates to a biothiol detecting composition comprising a redox regulation protein, a method for detecting biothiols by using the same, and a biosensor/kit for detecting biothiols. The present invention provides the effect of rapidly measuring free biothiols in body fluids. In addition, relative content ratios and changes of total to free biothiols in body fluids can be detected in real time, which allows biothiols to be available as main indices of diseases through which prediction and warning can be made against various diseases. Further, because various redox stress changes associated with main diseases can be accounted for by variations of biothiols, the present invention can provide important technical, economical, and social values for the investigation of pathogenesis mechanisms and the diagnosis of diseases in the future.