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1. (WO2018084124) COMPOSITION FOR PROMOTING SECRETORY IGA SECRETION

Pub. No.:    WO/2018/084124    International Application No.:    PCT/JP2017/039209
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Wed Nov 01 00:59:59 CET 2017
IPC: A61K 36/03
A61K 31/737
A61P 31/04
A61P 37/04
A61P 37/08
A61P 43/00
Applicants: KANEHIDE BIO CO.,LTD.
金秀バイオ株式会社
Inventors: MIYAGI, Mikio
宮城 幹夫
INAFUKU, Keiichiro
稻福 桂一郎
IKEHARA, Yukari
池原 ゆかり
Title: COMPOSITION FOR PROMOTING SECRETORY IGA SECRETION
Abstract:
The purpose of the present invention is to provide a composition which is highly safe and thus can be daily ingested and has an effect of continuously and age-independently promoting the secretion of s-IgA in saliva. For this purpose, provided are compositions for promoting secretory IgA secretion which comprise, as an active ingredient, fucoidan derived from Cladosiphon Okamuranus at a daily dose of 1,000 mg or more. These compositions have a mucosal immunopotentiating effect, anti-infective effect and anti-allergic effect. Therefore, it is hoped that the compositions are usable for ameliorating, relieving, suppressing, treating or preventing diseases and symptoms with a need for the aforesaid effects, for example, bacterial infections, viral infections, protozoal infections, food allergy, pollen allergy, gastritis, enteritis, diarrhea, ulcerative colitis, rhinitis, bronchitis, bronchial asthma, Loeffler's syndrome and stomatitis as well as symptoms thereof, or for immunotherapy and immune tolerance.