Search International and National Patent Collections
|1. (WO2018083538) ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND METHOD OF USE THEREOF|
|Applicants:||NEURACLE SCIENCE CO., LTD.
|Inventors:||CHUNG, Jun, Ho
YUNE, Tae Young
SEONG, Jae, Young
HWANG, Jong, Ik
JIN, Jun, Yeong
LEE, Jee, Youn
CHO, Eun, Bee
|Title:||ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND METHOD OF USE THEREOF|
The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.