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1. (WO2018083481) CANCER THERAPY

Pub. No.:    WO/2018/083481    International Application No.:    PCT/GB2017/053307
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Fri Nov 03 00:59:59 CET 2017
IPC: A61K 31/12
A61K 31/145
A61K 31/7135
A61K 33/34
A61P 35/02
Applicants: UCL BUSINESS PLC
Inventors: DE BOER, Jasper
CANTILENA, Sandra
Title: CANCER THERAPY
Abstract:
The present invention relates to the treatment of mixed lineage leukemia. In particular, the present invention relates to therapies involving the induction of proteolysis of the MLL fusion proteins that result from the chromosomal translocations affecting the MLL gene at 11q23.