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1. (WO2018083336) ACTIVATED LACTOBACILLUS REUTERI STRAINS FOR SELECTIVE PATHOGEN INHIBITION IN A HUMAN MICROBIAL COMMUNITY

Pub. No.:    WO/2018/083336    International Application No.:    PCT/EP2017/078463
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Wed Nov 08 00:59:59 CET 2017
IPC: A01N 63/02
A61K 35/747
C12N 1/04
A61P 31/04
Applicants: BIOGAIA AB
Inventors: ROOS, Stefan
SPINLER, Jennifer Kristine
Title: ACTIVATED LACTOBACILLUS REUTERI STRAINS FOR SELECTIVE PATHOGEN INHIBITION IN A HUMAN MICROBIAL COMMUNITY
Abstract:
Herein is disclosed a probiotic composition comprising cells of Lactobacillus reuteri preloaded with reuterin for use in the treatment or prevention of an infection caused by Clostridium difficile and/or other glycerol metabolizing pathogen(s) in an individual, and a method for the treatment or prevention of an infection caused by Clostridium difficile and/or other glycerol metabolizing pathogen(s) in an individual. Further provided is a method for manufacturing a composition comprising L. reuteri pre-loaded with reuterin, and compositions obtained by said method.