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1. (WO2018083314) USE OF PHENOTHIAZINE DERIVATIVE IN THE TREATMENT OF INFECTIOUS PURPURA OR PURPURA FULMINANS

Pub. No.:    WO/2018/083314    International Application No.:    PCT/EP2017/078370
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Tue Nov 07 00:59:59 CET 2017
IPC: A61K 31/5415
A61K 31/573
A61P 17/00
A61P 31/04
Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
UNIVERSITE PARIS DESCARTES
Inventors: BOURDOULOUS, Sandrine
DENIS, Kévin
LE GUENNEC, Loïc
Title: USE OF PHENOTHIAZINE DERIVATIVE IN THE TREATMENT OF INFECTIOUS PURPURA OR PURPURA FULMINANS
Abstract:
The present invention provides aphenothiazine derivative for use in preventing and/or treating infectious purpuraorpurpura fulminans, wherein infection is caused by a bacterium. The present invention further relates to a composition for the use in preventing and/or treatinginfectiouspurpura orpurpura fulminans comprising a phenothiazine derivative and an antibiotic selected in the group consisting of beta-lactams, aminoglycosides or dexamethasone.