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1. (WO2018083186) EARLY DETECTION OF PRELIMINARY STAGES OF TESTICULAR GERM CELL TUMORS

Pub. No.:    WO/2018/083186    International Application No.:    PCT/EP2017/078079
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Fri Nov 03 00:59:59 CET 2017
IPC: C12Q 1/6851
C12Q 1/6886
Applicants: MIRDETECT GMBH
Inventors: SPIEKERMANN, Meike
WINTER, Nina
BELGE, Gazanfer
RADTKE, Arlo
Title: EARLY DETECTION OF PRELIMINARY STAGES OF TESTICULAR GERM CELL TUMORS
Abstract:
The present invention relates to methods of detecting preliminary stages of testicular germ cell tumors, more particularly testicular intraepithelial neoplasia (TIN),in a subject and to the use of miR-371a-3p as a biomarker for the detection of TIN. It further relates to the use of miR-371a-3p-specific primers and/or miR-371a-3p-specific probes and of corresponding kits for the detection of TIN.