WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Options
Query Language
Stem
Sort by:
List Length
Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018083113) INSTANT RELEASE CAPSULE BASED ON HOT MELT EXTRUDED POLYVINYL ALCOHOL
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/083113 International Application No.: PCT/EP2017/077954
Publication Date: 11.05.2018 International Filing Date: 01.11.2017
IPC:
A61K 9/48 (2006.01) ,A61K 31/00 (2006.01) ,A61K 9/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
Applicants: MERCK PATENT GMBH[DE/DE]; Frankfurter Strasse 250 64293 Darmstadt, DE
Inventors: ZHENG, Mengyao; DE
KNUETTEL, Anja-Nadine; DE
Priority Data:
16197614.707.11.2016EP
Title (EN) INSTANT RELEASE CAPSULE BASED ON HOT MELT EXTRUDED POLYVINYL ALCOHOL
(FR) CAPSULE À LIBÉRATION INSTANTANÉE À BASE D'ALCOOL POLYVINYLIQUE EXTRUDÉ À CHAUD
Abstract:
(EN) The present invention relates to an improved powdered extrudate based on polyvinyl alcohol (PVA), which can be used for pharmaceutical products, and that, due to its improved properties, can be better filled into capsules and the capsules show stable immediate drug release kinetic without problem of particle aggregation. Furthermore, this invention refers to pharmaceutical capsule composition comprising extruded polyvinyl alcohol as carrier matrix and can improve the solubility of API within immediate release kinetic. Moreover, the capsule show also benefit than tablet regarding to the material cost, because just PVA and API, no additional excipients are needed for capsule.
(FR) La présente invention concerne un extrudat en poudre amélioré à base d'alcool polyvinylique (PVA), qui peut être utilisé pour des produits pharmaceutiques et qui, du fait de ses propriétés améliorées, permet de mieux remplir des capsules, et les capsules présentent une cinétique de libération immédiate de médicament stable sans problème d'agrégation de particules. En outre, la présente invention concerne une composition de capsule pharmaceutique comprenant l'alcool polyvinylique extrudé comme matrice de support et pouvant améliorer la solubilité de l'IPA (ingrédient pharmaceutique actif) dans une cinétique de libération immédiate. De plus, la capsule présente également un avantage par rapport au comprimé en ce qui concerne le coût du matériau, étant donné qu'il n'y a besoin que de PVA et d'IPA, sans aucun autre excipient pour la capsule.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)