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1. (WO2018083085) PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Pub. No.:    WO/2018/083085    International Application No.:    PCT/EP2017/077886
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Wed Nov 01 00:59:59 CET 2017
IPC: C07D 519/00
A61K 31/519
A61P 29/00
A61P 35/00
Applicants: F. HOFFMANN-LA ROCHE AG
GENENTECH, INC.
Inventors: BRYAN, Marian C.
DROBNICK, Joy
KIEFER, James Richard, Jr.
KOLESNIKOV, Aleksandr
RAJAPAKSA, Naomi S.
Title: PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
Abstract:
Compounds of Formula I and methods of use as Interleukin-1 Receptor Associated Kinase 4 (IRAK4) inhibitors are described herein.