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1. (WO2018083085) PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/083085    International Application No.:    PCT/EP2017/077886
Publication Date: 11.05.2018 International Filing Date: 31.10.2017
IPC:
C07D 519/00 (2006.01), A61K 31/519 (2006.01), A61P 29/00 (2006.01), A61P 35/00 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 4070 Basel (CH) (For All Designated States Except US).
GENENTECH, INC. [US/US]; 1 DNA Way South San Francisco, California 94080 (US) (US only)
Inventors: BRYAN, Marian C.; (US).
DROBNICK, Joy; (US).
KIEFER, James Richard, Jr.; (US).
KOLESNIKOV, Aleksandr; (US).
RAJAPAKSA, Naomi S.; (US)
Agent: SCHIRLIN, Julien; (CH)
Priority Data:
62/416,550 02.11.2016 US
62/417,893 04.11.2016 US
Title (EN) PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
(FR) DÉRIVÉS PYRAZOLO [1,5A]PYRIMIDINE EN TANT QUE MODULATEURS D’IRAK 4
Abstract: front page image
(EN)Compounds of Formula I and methods of use as Interleukin-1 Receptor Associated Kinase 4 (IRAK4) inhibitors are described herein.
(FR)L'invention concerne des composés de formule I et des procédés d'utilisation en tant qu'inhibiteurs de la kinase 4 associée au récepteur de l’Interleukin-1 (IRAK4).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)