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1. (WO2018083080) NKP46 LIGAND

Pub. No.:    WO/2018/083080    International Application No.:    PCT/EP2017/077864
Publication Date: Sat May 12 01:59:59 CEST 2018 International Filing Date: Wed Nov 01 00:59:59 CET 2017
IPC: G01N 33/50
G01N 33/569
Applicants: INNATE PHARMA
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE)
Inventors: NARNI-MANCINELLI, Emilie
GAUTHIER, Laurent
BARATIN, Myriam
VIVIER, Eric
Title: NKP46 LIGAND
Abstract:
This invention relates to natural ligands of NKp46 and compositions and methods for modulating NK-cell activation through NKp46 receptors. The compositions and methods can be used, in particular, for the treatment and diagnosis of disease in humans, for example cancers, infectious disease and inflammatory or autoimmune diseases.