A guide pin, comprising a base support layer (1) and a protective layer (2). The base support layer (1) is a rod-shaped structure. The protective layer (2) tightly wraps the surface of the base support layer (1). Also, a manufacturing method for the guide pin of various materials. The guide pin manufactured by employing the method is not prone to bending or deformation, has great properties in terms of corrosion resistance and acid/alkaline resistance, and is wear resistant, of an extended service life, easy to process, and inexpensive.