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1. (WO2018082151) MATRIX MATERIAL PROMOTING INDUCED DIFFERENTIATION OF BONE MARROW MESENCHYMAL STEM CELL INTO NERVE CELL
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Pub. No.: WO/2018/082151 International Application No.: PCT/CN2016/108356
Publication Date: 11.05.2018 International Filing Date: 02.12.2016
IPC:
C12N 5/0775 (2010.01) ,C12N 5/079 (2010.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
0775
Mesenchymal stem cells; Adipose-tissue derived stem cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
079
Neural cells
Applicants:
南方医科大学 SOUTHERN MEDICAL UNIVERSITY [CN/CN]; 中国广东省广州市 白云区沙太南路1023号 No.1023, South Shatai Road, Baiyun District Guangzhou, Guangdong 510515, CN
Inventors:
曾庆冰 ZENG, Qingbing; CN
文寒冰 WEN, Hanbing; CN
曾慧皋 ZENG, Huigao; CN
Agent:
北京市诚辉律师事务所 BEIJING CHENGHUI LAW FIRM; 中国北京市 朝阳区朝阳北路99号楼2单元905 905, Tower 2, No.99 Chaoyang North Road, Chaoyang District Beijing 100123, CN
Priority Data:
201610934377.301.11.2016CN
Title (EN) MATRIX MATERIAL PROMOTING INDUCED DIFFERENTIATION OF BONE MARROW MESENCHYMAL STEM CELL INTO NERVE CELL
(FR) MATÉRIAU MATRICIEL FAVORISANT LA DIFFÉRENCIATION INDUITE D'UNE CELLULE SOUCHE MÉSENCHYMATEUSE DE MOELLE OSSEUSE EN CELLULE NERVEUSE
(ZH) 一种促进骨髓间充质干细胞向神经诱导分化的基质材料
Abstract:
(EN) Provided is a support particle promoting differentiation of bone marrow mesenchymal stem cells into nerve cells. The support particle is a conjugate of a tobacco mosaic virus and an isoleucine-lysine-valine-alanine-valine pentapeptide (IKVAV). Also provided is a medium comprising the support particle.
(FR) L'invention concerne une particule de support favorisant la différenciation de cellules souches mésenchymateuses de moelle osseuse en cellules nerveuses. La particule de support est un conjugué d'un virus de la mosaïque du tabac et d'un pentapeptide isoleucine-lysine-valine-alanine-valine (IKVAV). L'invention concerne également un milieu comprenant la particule de support.
(ZH) 提供了一种促进骨髓间充质干细胞向神经分化的支架粒子,所述支架粒子为烟草花叶病毒与异亮氨酸-赖氨酸-缬氨酸-丙氨酸-缬氨酸五肽(IKVAV)的缀合物。还提供了包含所述支架粒子的培养基。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)