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1. (WO2018081944) COMPOSITION COMPOSED OF CEFTRIAXONE SODIUM AND SULBACTUM SODIUM
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/081944 International Application No.: PCT/CN2016/104327
Publication Date: 11.05.2018 International Filing Date: 02.11.2016
IPC:
A61K 31/546 (2006.01) ,A61K 31/43 (2006.01) ,A61P 31/04 (2006.01)
Applicants: XIANGBEI WELMAN PHARMACEUTICAL CO., LTD[CN/CN]; Liuyang Biomedical Park, Dongyang Town, Liuyang Changsha, Hunan 410331, CN
GUANGZHOU WELMAN NEW DRUG R&D CO., LTD.[CN/CN]; Room 1608, No.116, TiYuDong Road, Tianhe District Guangzhou, Guangdong 510620, CN
NANJING KANGFUSHUN PHARMACEUTICAL CO., LTD[CN/CN]; E3 Building, No.9, Weidi Road, Xianlin Street, Qixia District Nanjing, Jiangsu 210046, CN
Inventors: SUN, Mingjie; CN
Agent: CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED; 18th Floor, Tower B, CEC Plaza No. 3 Dan Ling Street,Haidian District Beijing 100080, CN
Priority Data:
Title (EN) COMPOSITION COMPOSED OF CEFTRIAXONE SODIUM AND SULBACTUM SODIUM
(FR) COMPOSITION COMPOSÉE DE CEFTRIAXONE SODIQUE ET DE SULBACTUM SODIQUE
Abstract:
(EN) A composition composed of ceftriaxone sodium and sulbactam sodium, a pharmaceutical formulation comprising the same and the application thereof. The composition is characterized in that specific diffraction angles are included in the X-ray powder diffraction analysis spectrum. The compositions and the pharmaceutical formulations have better antibacterial activity and stability as compared with existing formulations, and thus are suitable for the treatment of bacterial infections, especially urinary system infections caused by refractory Neisseria gonorrhoeae bacteria which have resistance to many antibiotics (β-lactams, tetracyclines, macrolides, fluoroquinolones and aminoglycosides).
(FR) L'invention concerne une composition composée de ceftriaxone sodique et de sulbactam sodique, une formulation pharmaceutique la comprenant et son application. La composition est caractérisée en ce que des angles de diffraction spécifiques sont inclus dans le spectre d'analyse de diffraction de rayons X sur poudre. Les compositions et les formulations pharmaceutiques ont une meilleure activité antibactérienne et une meilleure stabilité par comparaison avec les formulations existantes, et sont ainsi appropriées pour le traitement d'infections bactériennes, en particulier des infections du système urinaire provoquées par des bactéries Neisseria gonorrhoeae réfractaires qui ont une résistance à de nombreux antibiotiques (beta-lactames, tétracyclines, macrolides, fluoroquinolones et aminoglycosides).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)