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1. (WO2018081825) BENZOIMIDAZOL-1, 2-YL AMIDES AS KV7 CHANNEL ACTIVATORS

Pub. No.:    WO/2018/081825    International Application No.:    PCT/US2017/059393
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Wed Nov 01 00:59:59 CET 2017
IPC: C07D 235/30
C07D 401/12
C07D 413/04
C07D 405/12
C07D 403/04
A61K 31/4184
A61K 31/4427
A61K 31/5377
A61P 25/06
A61P 25/08
A61P 29/00
Applicants: KNOPP BIOSCIENCES LLC
Inventors: RESNICK, Lynn
TOPALOV, George, T.
BELARDI, Justin, K.
FLENTGE, Charles, A.
HALE, James, S.
MARESKA, David, A.
Title: BENZOIMIDAZOL-1, 2-YL AMIDES AS KV7 CHANNEL ACTIVATORS
Abstract:
Optionally substituted benzoimidazol-1,2-yl amides, such as compounds of Formula 1 or Formula 2, can be used to treat disorders associated with a Kv7 potassium channel activator. Compositions, medicaments, and dosage forms related to the treatment are also disclosed herein.