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1. (WO2018081652) AVATAR DENDRITIC CELLS: THE NEOANTIGEN NATURAL KILLER T-CELL CHEMO IMMUNO RADIATION COMPOSITION INDUCING IMMUNOGENIC CELL DEATH
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/081652    International Application No.:    PCT/US2017/058886
Publication Date: 03.05.2018 International Filing Date: 27.10.2017
IPC:
A61K 35/15 (2015.01), A61K 35/17 (2015.01), A61K 48/00 (2006.01), A61K 39/395 (2006.01), A61K 38/19 (2006.01)
Applicants: NANT HOLDINGS IP, LLC [US/US]; 9920 Jefferson Boulevard Culver City, California 90232 (US)
Inventors: SOON-SHIONG, Patrick; (US)
Agent: FESSENMAIER, Martin; (US).
SHIN, Minyoung; (US)
Priority Data:
62/414,207 28.10.2016 US
Title (EN) AVATAR DENDRITIC CELLS: THE NEOANTIGEN NATURAL KILLER T-CELL CHEMO IMMUNO RADIATION COMPOSITION INDUCING IMMUNOGENIC CELL DEATH
(FR) CELLULES DENDRITIQUES DE TYPE AVATAR COMPOSITION DE CHIMIO-IMMUNORADIOTHÉRAPIE À LYMPHOCYTES NK (CELLULES TUEUSES NATURELLES) DIRIGÉS CONTRE LES NÉOANTIGÈNES, INDUISANT UNE MORT CELLULAIRE IMMUNOGÈNE
Abstract: front page image
Contemplated compositions and methods counteract evasive measures of a tumor by rendering access to the tumor microenvironment, tagging the tumor microenvironment with chemoattractant and/or cytokines, delivering or facilitating a cell-based therapy in the tumor microenvironment while providing inhibition of immune suppressor cells in the tumor microenvironment.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)