Search International and National Patent Collections

1. (WO2018081638) NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN ADAPTIVE IMMUNE RESPONSE

Pub. No.:    WO/2018/081638    International Application No.:    PCT/US2017/058870
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Sat Oct 28 01:59:59 CEST 2017
IPC: A61K 39/145
A61K 39/21
A61K 39/39
A61K 9/51
A61K 47/18
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
ACUITAS THERAPEUTICS, INC.
Inventors: TAM, Ying
HOPE, Michael, J.
WEISSMAN, Drew
PARDI, Norbert
Title: NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN ADAPTIVE IMMUNE RESPONSE
Abstract:
The present invention generally relates to compositions and methods for inducing an adaptive immune response in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof.