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1. (WO2018081638) NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN ADAPTIVE IMMUNE RESPONSE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/081638 International Application No.: PCT/US2017/058870
Publication Date: 03.05.2018 International Filing Date: 27.10.2017
IPC:
A61K 39/145 (2006.01) ,A61K 39/21 (2006.01) ,A61K 39/39 (2006.01) ,A61K 9/51 (2006.01) ,A61K 47/18 (2017.01)
Applicants: WEISSMAN, Drew[US/US]; US
PARDI, Norbert[US/US]; US
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA[US/US]; 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104, US
ACUITAS THERAPEUTICS, INC.[CA/CA]; 6190 Agronomy Road, Suite 402 University of British Columbia - KETR Vancouver, British Columbia V6T 1W5, CA
Inventors: WEISSMAN, Drew; US
PARDI, Norbert; US
TAM, Ying; CA
HOPE, Michael, J.; CA
Agent: HARWOOD, Eric, A.; US
OBEIDAT, Baha, A.; US
KUMABE, Blake, K.; US
SOLTANI, Bobby, B.; US
SARGEANT, Brooke; US
QUIST, Brooke, W.; US
ROTH, Carol, J.; US
EIDT, Chandra, E.; US
O'BRIEN, Daniel; US
CARLSON, David, V.; US
STARK, Duncan; US
TARLETON, E., Russell; US
SUN, Eileen, S.; US
ABRAMONTE, Frank; US
HAN, Hai; US
TALBERT, Hayley, J.; US
CARTER, James, J.; US
WHITE, James, A. D.; US
BARRETT, Jared, M.; US
PEPE, Jeffrey, C.; US
DANLEY, Jeffrey, E.; US
SAKOI, Jeffrey, M.; US
BAUNACH, Jeremiah, J.; US
KARLEN, John, R.; US
MORGAN, John, A.; US
WAKELEY, John, J.; US
COE, Justin, E.; US
HENCKEL, Karen, M.; US
HEFTER, Karl, A.; US
HERMANNS, Karl, R.; US
MORGAN, Kevan, L.; US
COSTANZA, Kevin, S.; US
LINFORD, Lorraine; US
COOPER, Michael, P.; US
RUSYN, Paul; US
LIN, Qing; US
HALLER, Rachel, A.; US
IANNUCCI, Robert; US
KOVELMAN, Robert, L.; US
WEBB, Samuel, E.; US
LEEK, Shoko, I.; US
ROSENMAN, Stephen, J.; US
ABEDI, Syed; US
SATAGAJ, Thomas, J.; US
BOLLER, Timothy, L.; US
LIGON, Toby, J.; US
FERRON, William, O., Jr.; US
Priority Data:
62/413,83727.10.2016US
Title (EN) NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN ADAPTIVE IMMUNE RESPONSE
(FR) ARN À NUCLÉOSIDE MODIFIÉ DESTINÉ À INDUIRE UNE RÉPONSE IMMUNITAIRE ADAPTATIVE
Abstract: front page image
(EN) The present invention generally relates to compositions and methods for inducing an adaptive immune response in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof.
(FR) La présente invention concerne en général des compositions et des méthodes pour induire une réponse immunitaire adaptative chez un sujet. Dans certains modes de réalisation, la présente invention concerne une composition comprenant une molécule d'acide nucléique à nucléoside modifié, codant pour un antigène, un adjuvant, ou une combinaison de ceux-ci. Par exemple, dans certains modes de réalisation, la composition comprend un vaccin comprenant une molécule d'acide nucléique à nucléoside modifié, codant pour un antigène, un adjuvant, ou une combinaison de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)